Lack of sleep has a potentially harmful effect on gene expression, according to a study out on Aug. 6 that sheds light on the link between sleep deficits and a wide range of health conditions.
Lack of adequate shut-eye had already been linked to conditions from heart disease and cognitive impairment to obesity. But sleep researcher Derk-Jan Dijk and his fellow researchers have delved into the molecular mechanisms behind the phenomenon, looking at how missed sleep leads to health problems.
They found that a week of sleeping six hours or less a night affects the expression of some 711 genes, including those involved in inflammation, immunity, and stress responses.
Photo: REUTERS
照片:路透社
Compared with test subjects who were allowed to sleep as long as 10 hours a night, those who lacked sleep had irregularities in their genes’ circadian rhythms.
(AFP)
八月六日公布的一份研究說明睡眠不足與多項疾病的關聯性,根據研究,睡眠短缺可能有害基因表現。
缺乏足夠的闔眼已被與多項疾病連結,從心臟病、認知障礙到過胖等。但睡眠研究人員狄克與研究員同僚更深入這種現象背後的分子機制,研究睡眠不足如何導致健康問題。
他們發現,一週內每天睡眠不超過七小時,影響約七百十一種基因表現,包括與發炎、免疫、壓力反應等有關的基因。
此外,相較於一晚得以睡長達十小時的受試者,缺乏睡眠者的基因生理時鐘紊亂。
(法新社/翻譯:自由時報國際新聞中心)
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