People may soon be able to detect cancer at home using a simple kit that employs a gold nano-particle bio-sensing method, National Chia Tung University researchers said yesterday.
“Gold nano-particles [nanogold] are a substance that has been made since ancient times,” said Lin Chih-sheng (林志生), a professor at the university’s Institute of Molecular Medicine and Bioengineering.
“Suspended in buffer fluids, the minuscule particles of gold appear bright red,” Lin said, adding that nanogold could be used as a bio-sensor because it creates a solution when the particles are laden with other substances that changes color upon reaction with certain target bio-substances.
“For example, nanogold has been used in pregnancy test kits,” Lin said.
Last year, Lin and his students received the silver medal for the Industrial Development Bureau’s “2008 Crazy Idea King of Application — Biotechnology Research and Development Creative Application Competition” for developing nanogold into a detector capable of gauging matrix metalloproteinases (MMPs) abnormality in blood. The team’s paper has been accepted by several international journals, he said.
“Preliminary analysis has shown that MMPs, a protein, is closely related to tumor cell migration and invasion,” Lin said.
By definition, any tumor with self-limited growth is benign, whereas a tumor that transfers or migrates to other parts of the body is called cancer, Lin said.
“When coated with gelatin, gold nano-particles are separate in the buffer solution and appear red,” Lin’s team found.
“However, when gelatin-coated gold nano-particles encounter MMPs in the solution, the MMPs cut through the gelatin, which in turn exposes the nanogold so that the particles aggregate into bigger clusters and the solution turns a blue color,” he said.
Currently, MMP analysis in blood requires a lab zymography (usually in hospitals), which is complex and time-consuming, Lin said. If more studies can prove that MMPs indeed are related to tumor cell migration, his MMP bio-sensor could be developed into a simple kit to detect cancer.
“With a small drop of blood, people at risk will be able to do the test at home,” he said.
A magnitude 4.9 earthquake struck off Tainan at 11:47am today, the Central Weather Administration (CWA) said. The hypocenter was 32.3km northeast of Tainan City Hall at a depth of 7.3km, CWA data showed. The intensity of the quake, which gauges the actual effect of a seismic event, measured 4 in Tainan and Chiayi County on Taiwan's seven-tier intensity scale, the data showed. The quake had an intensity of 3 in Chiayi City and County, and Yunlin County, while it was measured as 2 in Kaohsiung, Nantou County, Changhua County, Taitung County and offshore Penghu County, the data showed. There were no immediate reports of
Weather conditions across Taiwan are expected to remain stable today, but cloudy to rainy skies are expected from tomorrow onward due to increasing moisture in the atmosphere, according to the Central Weather Administration (CWA). Daytime highs today are expected to hit 25-27°C in western Taiwan and 22-24°C in the eastern counties of Yilan, Hualien, and Taitung, data on the CWA website indicated. After sunset, temperatures could drop to 16-17°C in most parts of Taiwan. For tomorrow, precipitation is likely in northern Taiwan as a cloud system moves in from China. Daytime temperatures are expected to hover around 25°C, the CWA said. Starting Monday, areas
A Taiwanese software developer has created a generative artificial intelligence (AI) model to help people use AI without exposing sensitive data, project head Huang Chung-hsiao (黃崇校) said yesterday. Huang, a 55-year-old coder leading a US-based team, said that concerns over data privacy and security in popular generative AIs such as ChatGPT and DeepSeek motivated him to develop a personal AI assistant named “Mei.” One of the biggest security flaws with cloud-based algorithms is that users are required to hand over personal information to access the service, giving developers the opportunity to mine user data, he said. For this reason, many government agencies and
The National Fire Agency on Thursday said a series of drills simulating a magnitude 8.5 earthquake would be held in September to enhance the government’s emergency response capabilities. Since earthquakes cannot be predicted, only by continuously promoting disaster prevention measures could Taiwan enhance its resilience to earthquakes, agency Director-General Hsiao Huan-chang (蕭煥章) said in a news release. The exercises would be held to mark annual National Disaster Prevention Day on Sept. 21, the aim of which is to test Taiwan’s preparedness and improve its earthquake resilience in case of a major temblor, Hsiao said. As part of those drills, an earthquake alert would